Which sweat chloride value would be considered normal?

Prepare for the Neonatal/Pediatric Specialist Test. Use flashcards and multiple-choice questions with hints and explanations. Ready yourself for the exam!

Multiple Choice

Which sweat chloride value would be considered normal?

Explanation:
Sweat chloride testing gauges how well the CFTR chloride channel works in the sweat glands. Normal sweat has only a small amount of chloride; when CFTR is defective, chloride concentration in sweat rises. A value around 30 mmol/L falls within the normal range for this context, so it would be considered normal. The higher values (70, 100, 150 mmol/L) are clearly abnormal and would raise concern for CF. In CF testing, markedly elevated sweat chloride reflects failure of the CFTR channel to reabsorb chloride in sweat ducts, whereas normal values indicate typical CFTR function.

Sweat chloride testing gauges how well the CFTR chloride channel works in the sweat glands. Normal sweat has only a small amount of chloride; when CFTR is defective, chloride concentration in sweat rises.

A value around 30 mmol/L falls within the normal range for this context, so it would be considered normal. The higher values (70, 100, 150 mmol/L) are clearly abnormal and would raise concern for CF. In CF testing, markedly elevated sweat chloride reflects failure of the CFTR channel to reabsorb chloride in sweat ducts, whereas normal values indicate typical CFTR function.

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